Posted: By Skin IncThere is no such thing as a safe tan Lions Kerryon Johnson Jersey , U.S. and British researchers said on Thursday.They said in their review of published studies that tans and skin cancer both begin with DNA damage caused by exposure to ultraviolet light but many people, especially the young, ignore or are unaware of this danger in a quest for a bronzed body."The signals in the cells that induce sun tanning appear to be DNA damage," said Dorothy Bennett, a cell biologist at St. George's, University of London, who wrote one of the papers. "DNA damage is the first step in getting a mutation in cells that could lead to cancer, so there can't be anything like a safe tan."The World Health Organization estimates that as many as 60,000 people each year die from too much ultraviolet light Lions Frank Ragnow Jersey , mostly from malignant melanoma--the deadliest form of skin cancer. The link between skin cancer and damage from ultraviolet light from the sun or tanning booths is well known but the review published in the journal Pigment Cell & Melanoma Research suggests that even a little exposure is dangerous.Another problem is that while genetic and other factors also contribute to skin cancer risk, mixed messages about the safety of ultraviolet light confuses the public, Bennett added in a telephone interview. Getting some sunshine is important because ultraviolet light spurs the body to produce vitamin D. But people need far less ultraviolet exposure for this than it takes to tan, she said. "A lot of young people don't know about the scientific evidence," she said. "Anything that causes mutations in your cells increases your risk of cancer." Loading control antibodies are helpful for assessing western blotting efficiencies and comparing the amounts of protein loaded in each well across a gel. Theoretically, an ideal protein for an internal control should be the one that expresses at a constant level during the cell cycle, among different cell types and tissues at all stages of development, and unaffected by experimental treatments. Thus, housekeeping gene coded proteins Women's Jake Rudock Jersey , such as beta-actin and GAPDH, Tubulin are often chosen to serve this purpose. However, these commonly used loading controls are mostly suitable for animal samples.plant-animal-cell

The choice of appropriate housekeeping protein for plant sample would depend on the particular experiment and it needs to be confirmed. One has to determine a priority what does not change in one's test conditions and use that as a control. Another criteria to choose proper loading control is molecular weight, which means there should be at lease 5KD of molecular weight deference between target protein and loading control. Below loading controls are candidates for your particular research on plant samples.

Beta Actin

Actin is a highly conserved protein and an essential component of cell cytoskeleton and plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. Preferentially expressed in young and expanding tissues, floral organ primordia, developing seeds and emerging inflorescence. Arabidopsis has a complex actin gene family that encodes six protein subclasses. One of the classes is represented by the proteins ACT2 and ACT8 Women's Taylor Decker Jersey , which are similar proteins, but have different flanking sequences, introns and silent nucleotide positions in codons. ACT8 is expressed in root, stems, leaves, flowers, pollen and siliques.



Product Name Product Code Details
Anti-Plant Actin Mouse Monoclonal Antibody (3T3) A01050 Click here


The Anti-Plant Actin Mouse Monoclonal Antibody (3T3) is a monoclonal antibody raised from mouse host, with part of recombinant actin-11 protein as immunogen. It specifically detect Actin proteins from Arabidopsis, Nicotiana tabacum Women's Da'Shawn Hand Jersey , Oryza sativa, Hordeum vulgare, and we predicted it also work with other various specised , such as Brassica napus, Gossypium herbaceum, Solanum tuberosum, Setaria italic, Triticum monococcum, Brachypodium distachyon Women's Tracy Walker Jersey , Chrysanthemum seticuspe, Glycine max, Mangifera, Thellungiella halophila, Zoysia japonica, Isatis tinctoria based on immunogen sequence.

Rubisco (Large Chain)

Rubisco (Ribulose-1,5-bisphosphate carboxylaseoxygenase) catalyzes the rate-limiting step of CO2 fixation in photosynthetic organisms. It is demonstrably homologous from purple bacteria to flowering plants and consists of two protein subunits, each present in 8 copies. In plants and green algae, the large subunit (~55 kDa) is coded by the chloroplast rbcL gene Women's Graham Glasgow Jersey , and the small subunit (15 kDa) is coded by a family of nuclear rbcS genes.



Product Name Product Code Details
Anti-Rubisco (Large Chain) Monoclonal Antibody (9Y6) A01110 Click here
Rubisco Polyclonal Antibody ABM40182 Click here


This Anti-Rubisco (Large chain) monoclonal antibody (9Y6) is a monoclonal antibody raised from mouse host, with part of recombinant Rubisco large unite protein as immunogen. It specifically recognizes plants endogenous Rubisco Large Chain proteins in various plants. Another Rubisco (Large chain) polyclonal antibody are also provided in case you need rabbit hosted antibody with high affinity.

We develop and produce full portfolio of loading control antibodies, such as GAPDH, Beta-Actin, GAPDH, PCNA, Histone H3, Tubulun, Lamin B1 Women's A'Shawn Robinson Jersey , Cyclophilin B, COX IV, etc, and tag antibodies, such as His, HA, Flag, MBP, mCherry Women's Michael Roberts Jersey , GST, GFP, V5, VSV-G, Digoxin, Ubiquitin, BGF, RFP,mOrange Women's Jalen Reeves-Maybin Jersey , AmCyan, T7, Strep, S tag, KT3, etc, which have been commonly used around world. Abbkine is committed to reducing the cost of research with value, integrity and a truly personal buying experience. Products are available from affordable research quantities to larger bulk amounts for process development and production.
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